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Prevention and Treatment of Neonatal Infections in Facility and Community Settings of Low- and Middle-Income Countries: A Descriptive Review.

Neonatology · 2025 · PMC11875423 · PMID 39532080

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In contrast, bovine lactoferrin supplementation dosages of 80–142 mg/kg per day, compared to placebo, significantly reduced the risk of sepsis-attributable mortality (i.e., death of neonates with culture-proven LOS) by 7.5% ( p = 0.027) and reduced the risk of first episodes of culture-proven sepsis by 79% (95% CI to 96% decrease to 2% increase), though this finding did not reach statistical significance [ 89 ].

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