In the multiple regression analysis with SLEDAI-2K as the dependent variable and BMI and IFN-alpha as covariates, while the results did not reach statistical significance, BMI exhibited a tendency toward a greater absolute t-value compared to IFN-alpha ( Supplementary Table 3 ).
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Body weight in systemic lupus erythematosus is associated with disease activity and the adaptive immune system, independent of type I IFN.
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