Barely Significant
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Identification of plasma proteomic markers underlying polygenic risk of type 2 diabetes and related comorbidities.

Nat Commun · 2025 · PMC11876343 · PMID 40032831

Europe PMCDOI
1
hedged sentence
0.0300
closest p · 0.6× alpha
0.0300
boldest claim

The sentences

nominally significantp -value = 0.03actually significant
When adjusting for clinical risk factors, 6 proteins were significantly associated with either MACE or HHF (FDR-adjusted p -value < 0.05), while for the time to DECLARE’s composite renal outcome, IGFBP6 was nominally significant ( p -value = 0.03; Fig. 4C–E ).

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