Inhibition of platin-induced BCL2 increase overcomes chemoresistance in squamous cell carcinoma of the head and neck through resensitization to cell death.

Transl Oncol · 2025 · PMC11880736 · PMID 39970625

Europe PMC DOI

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closest p

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did not reach statistical significanceno p-value reported

Although this did not reach statistical significance, we would like to mention this positive trend of reversed EMT in both HNSCC16 and HNSCC46 cells.

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highly significantno p-value reported

While this was highly significant in HNSCC16 and HNSCC46, no such therapeutic effects were detectable in the BCL2 high HNSCC48 cells, which were classified as resistant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.