Additionally, we also investigated the prognostic value of UBA1/6 in pan-cancer from GEO database, and discovered that elevated UBA1 expression in breast cancer ( GSE1456 ), gastric cancer ( GSE14210 ), and myeloma ( GSE24080 ) is associated with a poorer prognosis, whereas higher UBA1 expression correlates with a more favorable prognosis in colon cancer ( GSE1258 )., Notably, the relationship between UBA6 expression and prognosis did not reach statistical significance in the aforementioned dataset.
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Multi-omics analysis identifies UBA family as potential pan-cancer biomarkers for tumor prognosis and immune microenvironment infiltration.
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