Impact of maternal smoking and secondhand smoke exposure during singleton pregnancy on placental abruption: analysis of a prospective cohort study (the Japan Environment and Children's Study).

In Model 2, when pregnant women with SHS exposure of almost never or never were set as a reference category, the aPAFs were 0.91% (95% CI −6.81% to 8.63%) in those with SHS exposure of 1–3 days/week and/or <1 hour/day and 3.09% (95% CI −0.16% to 6.33%) in those with SHS exposure of 4–7 days/week and ≥1 hour/day, respectively, which slightly failed to reach significance.

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The aPAF for pregnant women with SHS exposure of 4–7 days/week and ≥1 hour/day among never-smokers slightly did not reach statistical significance but tended to have a high risk of placental abruption, which aPAF was 1.89% (95% CI −0.05% to 3.83%).

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