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Human placental mesenchymal stem cells ameliorates premature ovarian insufficiency via modulating gut microbiota and suppressing the inflammation in rats.

PLoS One · 2025 · PMC11882084 · PMID 40043087

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What specific aspects of PMSC treatment are believed to account for its superior efficacy compared to conventional hormone therapy? Hormonal Regulation: While E2 levels were improved by PMSC intervention, they did not reach statistical significance compared to the control.

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