Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) of Extraperitoneal Abdominal Disease, is it Appropriate?

Ann Surg Oncol · 2025 · PMC11882691 · PMID 39904847

Europe PMC DOI

hedged sentence

0.0610

closest p · 1.2× alpha

0.0610

boldest claim

The sentences

approached significancep = 0.061so close (0.05 < p ≤ 0.1)

Furthermore, DFS times and 5-year DFS rates did not statistically differ between the cohorts; however, for PFS, the AEC cases exhibited longer survival times that approached significance ( p = 0.061), and 5-year PFS rates were statistically improved at 13.6% versus 2.2% (OR 6.87, 95% CI 1.073–43.978, p = 0.021).

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