Genetic variation in RYR1 is associated with heart failure progression and mortality in a diverse patient population.

Front Cardiovasc Med · 2025 · PMC11885062 · PMID 40060969

Europe PMC DOI

hedged sentence

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

did not reach statistical significanceP = 0.08so close (0.05 < p ≤ 0.1)

A mortality trend consistent with the overall cohort was also observed for rs2915950 in the Black subset; however, it did not reach statistical significance (HR = 0.67, 95% CI: 0.43–1.05, P = 0.08).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.