GABA and GLP-1 receptor agonist combination therapy modifies diabetes and Langerhans islet cytoarchitecture in a rat model of Wolfram syndrome.

Diabetol Metab Syndr · 2025 · PMC11887366 · PMID 40050934

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did not reach statistical significanceno p-value reported

Saline treated Wfs1 KO animals showed a threefold reduction in β-cell mass and a fourfold increase in δ-cell mass, while the increase in α-cell mass did not reach statistical significance, aligning with our previous findings [ 34 ].

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