Gut microbiota alteration was related to subclinical hypothyroidism and dyslipidemia in mice.

As shown in Figure 2E,F , ACE index and Chao 1 index, which all reflect species richness, indicated increasing trends in SCH mice relative to control mice, though these differences did not reach statistical significance.

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Compared with the MMI group, which presented subclinical hypothyroidism, the serum FT4 level in the ABXMMI group exhibited a decreasing trend, and the serum TSH level exhibited an increasing trend, although these differences did not reach statistical significance.

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