Consensus molecular subtyping of colorectal carcinoma brain metastases reveals a metabolic signature associated with poor patient survival.

Mol Oncol · 2025 · PMC11887667 · PMID 39825568

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did not quite reach statistical significanceno p-value reported

In line, the same trend was observed for IHC‐based protein expression of the seven markers in the validation cohort, although it did not quite reach statistical significance when tested as a negative survival predictor (HR (high) = 2.68 [0.88–8.14], P (HR) = 0.082) (Fig.

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did not reach statistical significanceno p-value reported

In patients with CRC brain metastases, CMS3 classification was associated with the poorest survival probabilities when compared to CMS1 and CMS2, although it did not reach statistical significance when tested as a predictive marker (HR (CMS3) = 2.026, P (HR) = 0.138).

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