BDNF and TRiC-inspired reagent rescue cortical synaptic deficits in a mouse model of Huntington's disease.

Neurobiol Dis · 2024 · PMC11890210 · PMID 38608784

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hedged sentences

0.0092

closest p · 0.2× alpha

0.0530

boldest claim

The sentences

highly significantp = 0.0092actually significant

The reduction in BACHD versus WT neurons in the % of Synapsin I/PSD95 over time was highly significant ( p = 0.0092) ( Fig. 5C ).

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a strong trendp = 0.053so close (0.05 < p ≤ 0.1)

When compared to WT neurons, BACHD neurons showed a significant decrease in the % of PSD95/Synapsin I at DIV14 ( p = 0.0002), DIV21( P < 0.0001), and DIV35 (P < 0.0001) and a strong trend to a decrease at DIV28 ( p = 0.053) ( Fig. 5B , Table 1 ).

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