The influence of genetic polymorphisms on cytokine profiles in pediatric COVID-19: a pilot study.

Front Pediatr · 2025 · PMC11891370 · PMID 40066463

Europe PMC DOI

hedged sentences

0.0170

closest p · 0.3× alpha

0.0170

boldest claim

The sentences

highly significantp = 0.017actually significant

The ACE2 rs2074192 variant notably exhibited a highly significant positive association with IL-6 levels (B = 110.74, p = 0.017) and IL-8 levels (B = 18.05, p = 0.004).

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did not reach statistical significanceno p-value reported

However, the models for IL-1β, IL-6, IL-8, IL-12, and TNF-α did not reach statistical significance ( Table 7 ).

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