Role of vitamins in the pathogenesis and treatment of restless leg syndrome: A systematic review and meta-analysis.

PLoS One · 2025 · PMC11892881 · PMID 40063620

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hedged sentence

0.0600

closest p · 1.2× alpha

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boldest claim

The sentences

did not reach statistical significanceP = 0.06so close (0.05 < p ≤ 0.1)

The difference, however, was that folate levels in pregnant RLS women were lower than those in healthy pregnancy controls, but did not reach statistical significance (MD = -4.23; 95% CI = -8.57 to 0.11, P = 0.06; heterogeneity, I 2 = 94%; P < 0.00001) (Supplement Fig 2b).

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