Sleep is necessary for experience-dependent sequence plasticity in mouse primary visual cortex.

Experimental mice showed significant plasticity between morning (M) and evening (E) sessions ( Figure 2C and D ; one-way RM ANOVA, F (1.333,12) = 25.53, p = .0001; post hoc ABCD (M)—ABCD (E): p = .0010; ABCD (M)—DCBA (E): p = .0013; ABCD (E)—DCBA (E): p = .0105), while control mice showed a trend towards slightly increased VEP magnitude ( Figure 2C and D ; one-way RM ANOVA, F (1.936,17.42) = 3.690, p = .0473, post hoc ABCD (M1)—ABCD (M2): p = .0611; ABCD (M)—DCBA (E): p = .1161; ABCD (E)—DCBA (E): p = .9622).

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