Dynamic HER2-low status among patients with triple negative breast cancer (TNBC) and the impact of repeat biopsies.

NPJ Breast Cancer · 2025 · PMC11897376 · PMID 40069204

Europe PMC DOI

hedged sentence

0.4500

closest p · 9.0× alpha

0.4500

boldest claim

The sentences

did not reach statistical significancep = 0.45not close (p > 0.1)

While the observed discordance in HER2 status between core-surgical matched Bxs or between two metastatic matched Bxs did not reach statistical significance ( p = 0.45 and p = 0.3, respectively), significant discordance in HER2 status was observed between early-metastatic matched biopsies ( p = 0.026; Fig. 3b ).

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