Inhibition of TIGIT on NK cells improves their cytotoxicity and HIV reservoir eradication potential.

mBio · 2025 · PMC11898710 · PMID 39918313

Europe PMC DOI

hedged sentences

0.0575

closest p · 1.1× alpha

0.0649

boldest claim

The sentences

did not reach statistical significanceP = 0.0575so close (0.05 < p ≤ 0.1)

Although the relationship between IFN-γ and HIV msRNA concentrations did not reach statistical significance, there was a trend toward an inverse association ( r = −0.4208, P = 0.0575) ( Fig. 2B ).

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a notable trendP = 0.0649so close (0.05 < p ≤ 0.1)

Moreover, there was a notable trend, the HIV-infected individuals with a lower percentage of TIGIT + NK cells and a higher percentage of CD226 + NK cells had lower concentrations of HIV msRNA ( P = 0.0649) ( Fig. 4B ).

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