Rotenone Induces Parkinsonism with Constipation Symptoms in Mice by Disrupting the Gut Microecosystem, Inhibiting the PI3K-AKT Signaling Pathway and Gastrointestinal Motility.

Int J Mol Sci · 2025 · PMC11899888 · PMID 40076704

Europe PMC DOI

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closest p · 1.0× alpha

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boldest claim

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did not reach statistical significancep > 0.05actually significant

Lactobacillaceae , Muribaculaceae , and Saccharimonadaceae also exhibited a significant decrease in relative abundance in the rotenone group, though this decrease did not reach statistical significance ( p > 0.05).

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