Barely Significant
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The efficacy of Sarcomeal® oral supplementation plus vitamin D3 on muscle parameters, metabolic factors, and quality of life in diabetic sarcopenia: a randomized controlled clinical trial.

Aging Clin Exp Res · 2025 · PMC11903600 · PMID 40075050

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As can be seen, while the mean skeletal muscle index significantly improved over 12 weeks in the intervention group (change [95% CI]: 0.17 [0.016, 0.329] kg/m2; p < 0.05), the difference in the two groups did not reach statistical significance (mean difference [95% CI]: 0.15 [-0.05, 0.37] kg/m2; P: 0.14).

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