Endometrium-derived organoids from cystic fibrosis patients and mice as new models to study disease-associated endometrial pathobiology.

Exposure of CFEO to the CFTR modulator combination ETI showed a trend of restoring swelling upon FSK treatment, although variable along different CFEO lines and non-significant (Fig. 2 E), all in line with recent findings in CF nasal organoids [ 37 ] and likely also due to the highly pre-swollen CFEO phenotype at the start.

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