Barely Significant
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Trends in opioid dispensing to injured workers following codeine scheduling changes in Australia: a retrospective cohort study.

BMJ Open · 2025 · PMC11904360 · PMID 40074256

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a significant trendno p-value reported
There was a significant 28.5% (99% CI 16.3, 41.9) step increase (ie, increase immediately after up-scheduling) in high-dose (>15 mg) codeine with a significant trend decrease (−1.3%, 99% CI −2.5, –0.2).

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