In addition, liver stiffness also did not correlate with serum Neuregulin1α levels, although patients with liver fibrosis showed a trend towards lower serum Neuregulin1α levels when compared to those without liver fibrosis (Supplementary Fig. 6e, f and Supplementary Table 5 , 6 ).
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Liver-derived Neuregulin1α stimulates compensatory pancreatic β cell hyperplasia in insulin resistance.
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