Barely Significant
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Comparison of flares in 85 patients with SLE who maintained, discontinued or reduced dose of hydroxychloroquine during a prospective study of ophthalmological screening for retinopathy (PERFOCTAPS Study).

Lupus Sci Med · 2025 · PMC11907073 · PMID 40081891

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The same trend was observed in the discontinuation group, but did not reach statistical significance, likely because of the small sample (adjusted HR 1.78; 95% CI 0.41 to 7.71).

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