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Investigating the impact of multidimensional sleep traits on cardiovascular diseases and the mediating role of depression.

Open Heart · 2025 · PMC11907084 · PMID 40086821

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In addition, we also found that although the mediation proportion of MDD did not reach statistical significance in the effects of insomnia on stroke, sleep duration on CAD, MI and HF, daytime napping on HF and daytime sleepiness on CAD, the mediation effect of MDD in the foregoing associations was significant, which indicated that MDD might act as a mediator in the foregoing causal pathway.

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