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Critical Roles of VEGFR1, VEGFR2, VEGFR3, BAX, and BCL-2 in the Pathogenesis of Varicose Veins: Unveiling Molecular Mechanisms.

Am J Mens Health · 2025 · PMC11907509 · PMID 40079569

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Although this value did not reach statistical significance, a BAX/BCL-2 ratio greater than 1 traditionally signals a shift toward pro-apoptotic signaling, as BAX induces apoptosis while BCL-2 inhibits it.

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