Barely Significant
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Metrnl ameliorates myocardial ischemia-reperfusion injury by activating AMPK-mediated M2 macrophage polarization.

Mol Med · 2025 · PMC11907862 · PMID 40082768

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a clear trendno p-value reported
Regrettably, Metrnl did not show a clear trend towards pro-M2 macrophage polarization on an M2 macrophage basis.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.