However, because only patients with an established trend of lesion expansion are suitable for the trial, a thorough pretrial screening process is necessary.
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Evolution of Chronic Lesion Tissue in Relapsing-Remitting Patients With Multiple Sclerosis: An Association With Disease Progression.
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The sentences
The difference between the 2 groups remained highly significant after adjusting the analysis for the volume of new lesions, indicating a considerable contribution of CLT expansion to brain tissue loss.
The difference in ventricle volumes demonstrated borderline significance.