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Enhancing AAV-microdystrophin gene therapy after repeat dosing by blocking phagocytosis.

Front Immunol · 2025 · PMC11911185 · PMID 40098958

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The average relative fluorescent signal following rAAV9-microdystrophin and combination treatment was reduced by 26% (19669 ± 3526) compared to rAAV9-microdystrophin treated mice (26468 ± 3644), but this did not reach statistical significance ( Supplementary Figure 3 ).

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