The in-hospital administration of sacubitril/valsartan in acute myocardial infarction: A meta-analysis.

ESC Heart Fail · 2025 · PMC11911573 · PMID 39473218

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

a trend towards significanceP value = 0.07so close (0.05 < p ≤ 0.1)

Similarly, patients who received ARNis had lower rates of MACE (OR 0.38, 95% CI 0.19–0.35, P value = 0.005) and a trend towards significance for HF rehospitalizations (OR 0.30, 95% CI 0.08–1.08, P value = 0.07) compared with those who received ARBs.

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a strong trendno p-value reported

Left ventricular volumes were significantly lower in the ARNi group and there was a strong trend towards an increase in left ventricular ejection fraction (LVEF) in this group.

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