IL-4 mediated TAP2 downregulation is a dominant and reversible mechanism of immune evasion and immunotherapy resistance in non-small cell lung cancer.

Mol Cancer · 2025 · PMC11912681 · PMID 40091029

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

showed a trendno p-value reported

1 E, tumors with TAP2 downregulation alone showed a trend towards lower CD8 + TILs (range 6.6–33.3%) that reached statistical significance only in cohorts #1 and #3.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.