GH Therapy in Chronic Heart Failure: A Systematic Review and Meta-analysis of Randomized Controlled Trials.

J Clin Endocrinol Metab · 2025 · PMC11913100 · PMID 39566897

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0.1000

closest p · 2.0× alpha

0.1000

boldest claim

The sentences

did not reach statistical significanceP = .1so close (0.05 < p ≤ 0.1)

However, global effect sizes did not reach statistical significance for peak work (1.39; 95% CI, −0.29 to 3.06; P = .1), exercise duration (0.43; 95% CI, −0.46 to 1.32; P = .35), IVSd (0.44; 95% CI, −0.27 to 1.15; P = .22), LVPWd (0.75; 95% CI, −0.03 to 1.52; P = .06), HR (0.36; 95% CI, −0.16 to 0.88; P = .18), and DBP (−0.45; 95% CI, −1.23 to 0.32; P = .25).

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a nonsignificant trendno p-value reported

Despite the positive outcomes for VO2max, statistical significance was not achieved for peak work and exercise duration, although a nonsignificant trend toward improvement was observed.

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