Motion Syros: tradipitant effective in the treatment of motion sickness; a multicenter, randomized, double-blind, placebo-controlled study.

Front Neurol · 2025 · PMC11913704 · PMID 40103934

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a slight trendno p-value reported

However, there was a slight trend toward favoring both tradipitant treatment groups over placebo.

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did not reach statistical significanceno p-value reported

PGI-S scores were also lower in the 170 mg tradipitant group (LS mean difference = −0.1, 95% CI: −0.42, 0.23, p = 0.5542) and the 85 mg tradipitant group (LS mean difference = −0.2, 95% CI: −0.49, 0.15 p = 0.3025) compared to placebo, but did not reach statistical significance.

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