Comparing the OS of LUD2015-005 patients with that of a propensity-matched cohort of CTX-treated patients from SEER, 33 a US-based registry of cancer cases, suggested a potential trend toward increased OS in the LUD2015-005 cohort, but this trend did not reach statistical significance, possibly due to the small cohort size of LUD2015-005 ( Figure S1 A).
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Tumor monocyte content predicts immunochemotherapy outcomes in esophageal adenocarcinoma.
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In contrast, in single-timepoint analyses of ICI-4W biopsies, many genes showed highly significant associations with ICI-induced changes in tumor burden.