Rutin attenuates bleomycin-induced acute lung injury <i>via</i> miR-9-5p mediated NF-κB signaling inhibition: network pharmacology analysis and experimental evidence.

Front Pharmacol · 2025 · PMC11920148 · PMID 40110126

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hedged sentence

0.0850

closest p · 1.7× alpha

0.0850

boldest claim

The sentences

borderline non-significantp = 0.085so close (0.05 < p ≤ 0.1)

Although rutin treatment at a dose of 100 mg produced a borderline non-significant decrease in the lung index by 15.67% ( p = 0.085), the treatment with the higher dose was able to reduce the lung index significantly by 30.41% ( p = 0.001) compared to the BLM-intoxicated group ( Figure 5A ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Rutin attenuates bleomycin-induced acute lung injury &lt;i&gt;via&lt;/i&gt; miR-9-5p mediated NF-κB signaling inhibition: network pharmacology analysis and experimental evidence.

The sentences

Rutin attenuates bleomycin-induced acute lung injury <i>via</i> miR-9-5p mediated NF-κB signaling inhibition: network pharmacology analysis and experimental evidence.