Outcomes of Deferring Percutaneous Coronary Intervention Without Physiologic Assessment for Intermediate Coronary Lesions.

In the Fractional Flow Reserve versus Angiography for Multivessel Evaluation (FAME) 2 trial, medical arm had a strong trend towards a higher risk of cardiac death or MI compared to PCI arm, Additionally, the medical arm experienced a significantly higher frequency of MIs beyond the initial period of follow-up. 4) However, it is important to note that there are differences in the inclusion criteria and patient populations between the studies mentioned and SMART-CASE trial.

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