DNA methylation heterogeneity correlates with field cancerization and prognosis in lung adenocarcinoma patients.

Clin Epigenetics · 2025 · PMC11924610 · PMID 40114223

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

did not reach statistical significanceP = 0.080so close (0.05 < p ≤ 0.1)

1.99 mut/MB), although the difference did not reach statistical significance ( P = 0.080, Supplemental Figure S3F).

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an increasing trendno p-value reported

The tumor mutational burden (TMB) also showed an increasing trend in the C2 subtype (4.99 vs. 1.99 mut/MB), although the difference did not reach statistical significance ( P = 0.080, Supplemental Figure S3F).

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