plant -EVs increased, the expression of cytochrome C (CytC), Cleaved-Caspase 3, and Cleaved-Caspase 9 showed a decreasing trend, providing further evidence that L. plant -EVs effectively alleviate apoptosis via the mPTP-CytC-Caspase pathway (Fig. 3 f).
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Reducing severity of inflammatory bowel disease through colonization of Lactiplantibacillus plantarum and its extracellular vesicles release.
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plant -EVs showed a trend of alleviating body weight loss (Fig. 2 f and g) and improving colon shortening (Fig. 2 h) in the IBD mouse model, although without reaching statistical significance.