In contrast with males, the 5-HIAA/5-HT turnover ratio showed a trend of increase in females receiving an infusion of 1 pmol AβOs, and a significant increase induced by infusion of 10 pmol AβOs, which was not observed in females submitted to neonatal MS (Fig. 3 F).
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Neonatal maternal separation causes depressive-like behavior and potentiates memory impairment induced by amyloid-β oligomers in adult mice.
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