Cyclin E1 overexpression triggers interferon signaling and is associated with antitumor immunity in breast cancer.

J Immunother Cancer · 2025 · PMC11927439 · PMID 40101803

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Notably, tumors with high cyclin E1 mRNA expression correlated with two “brisk” patterns, and the CCNE1 copy number gain group also showed a trend towards an increased proportion of “brisk band-like” patterns of TILs ( figure 2A,B ).

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