The chemotherapy agent doxorubicin induces CNS expression of Ascl1, a regulator of adult neurogenesis and differentiation.

Sci Rep · 2025 · PMC11928606 · PMID 40118985

Europe PMC DOI

hedged sentence

0.0740

closest p · 1.5× alpha

0.0740

boldest claim

The sentences

did not reach statistical significancep = 0.074so close (0.05 < p ≤ 0.1)

A similar pattern of the effect of doxorubicin was seen in an increase in the number of cells in the subgranular zone of the dentate gyrus expressing Ascl1-TdTomato (33%), but this difference did not reach statistical significance ( p = 0.074, t = 1.91, df = 16).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.