Unraveling the immune-activated tumor microenvironment correlated with clinical response to atezolizumab plus bevacizumab in advanced HCC.

JHEP Rep · 2025 · PMC11929055 · PMID 40124166

Europe PMC DOI

hedged sentence

0.1100

closest p · 2.2× alpha

0.1100

boldest claim

The sentences

did not reach statistical significancep = 0.11not close (p > 0.1)

The analysis of number of T cells (abundance) sharing unique CDR3 (Clone ID) indicated an increase in clonality score (Gini index) within CD8 T cells (C6–C9 clusters) in the responder group, although this did not reach statistical significance ( p = 0.11) because of the small sample size ( Fig. 2 B,C).

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