Global, regional and national burden of rheumatoid arthritis from 1990 to 2021, with projections of incidence to 2050: a systematic and comprehensive analysis of the Global Burden of Disease study 2021.

In contrast, Southern Sub-Saharan Africa, High-income Asia Pacific, and Tropical Latin America were the only three regions to show a decreasing trend (Table S1, Figure S2).

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There were significant differences in the number of cases and age-specific rates among different age groups, but they all showed a trend of first increasing and then decreasing with age.

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