Targeting Respiratory Viruses: The Efficacy of Intranasal mRNA Vaccination in Generating Protective Mucosal and Systemic Immunity Against Influenza A (H1N1).

Influenza Other Respir Viruses · 2025 · PMC11932742 · PMID 40127967

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moderately significantp < 0.01actually significant

The mRNA‐MHCS‐LNPs stored at 4°C showed a moderately significant ( p < 0.01, two‐way ANOVA) decrease in encapsulation efficiency from Day 0 (95.13%) to Day 30 (91.15%), and the mRNA‐MHCS‐LNPs stored at −20°C showed no significant mRNA leakage during the storage period (Figure 3c ).

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