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Engineering an optimized hypercompact CRISPR/Cas12j-8 system for efficient genome editing in plants.

Plant Biotechnol J · 2025 · PMC11933828 · PMID 39799585

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Our findings indicate that substituting certain crRNA‐interacting residues with positively charged arginine led to a 1.3‐fold increase in genome editing activity, though this result did not reach statistical significance for the targets tested.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.