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Branching Ionizable Lipids Can Enhance the Stability, Fusogenicity, and Functional Delivery of mRNA.

Small Sci · 2023 · PMC11935957 · PMID 40212983

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When the regressed microviscosity values were plotted against each of the physicochemical characteristics, a clear trend was identified as the LNPs with higher microviscosity had smaller particle sizes with lower PDI and improved encapsulation efficiency (Figure 3f–h ).

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