Integrative multi-omics analysis and machine learning refine global histone modification features in prostate cancer.

Front Mol Biosci · 2025 · PMC11936803 · PMID 40144021

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a clear trendno p-value reported

In the MSKCC cohort ( Figure 5G ), high Gleason scores (HR = 9.255, 95% CI: 4.361–19.54, P < 0.001) were statistically significant, while CMLHMS scores (HR = 1.91, 95% CI: 0.877–4.16, P = 0.1034) indicated a clear trend toward increased risk.

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