Exposure to sevoflurane significantly decreased the expression of Olig2 protein in the hippocampal region of mice during lactation and adolescence (t=4.064, p=0.0153) (t=2.946, p=0.0421), as well as in the prefrontal cortex of mice during these same periods (t=8.242, p=0.0012) (t=5.491, p=0.0654), although this latter p-value approached significance.
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The role of intestinal homeostasis in sevoflurane-induced myelin development and cognitive impairment in neonatal mice.
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