The treatments did not change the proportion of tumor-specific CD8 + T cells in circulation or in the tumor, however, the absolute number showed a trend of increase in the tumor of mice from the anti-PD-1 and the combination treatment groups ( online supplemental figure S11 ).
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Selective activation of interleukin-2/interleukin-15 receptor signaling in tumor microenvironment using paired bispecific antibodies.
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