The Prognostic, Predictive and Clinicopathological Implications of KRT81/HNF1A- and GATA6-Based Transcriptional Subtyping in Pancreatic Cancer.

Only KRT81/HNF1A-based subtypes showed a trend towards statistical significance in multivariate analyses ( p = 0.07, Supplementary Table S8 ) and transcriptional subtypes were not associated with the patients’ clinicopathological variables ( Table 1 ).

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This was not associated with synchronous or metachronous metastasis ( Supplementary Table S4 ) but came with a highly significant trend towards a prognostically more favorable subtype ( Supplementary Table S5 ).

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